Ca 1725 Ephraim married Elizabeth Spring.
Children of Ephraim and Elizabeth (Spring) Whitmore, born at Killingly:
i. Lois Whitmore, b. 29 Oct 1726;
ii. Jaazariah Whitmore, b. 8 Apr 1729;
iii. Elijah Whitmore, b. 1 Jul 1731;
iv. Asa Whitmore, b. 4 Oct 1733;
v. Elisha Whitmore, b. 2 May 1738;
vi. Patience Whitmore, b. 5 Jun 1740;
vii. Elizabeth Whitmore, b. 28 Aug 1742;
viii. Mary Whitmore, b. 15 Jul 1744; and
ix. Ephraim Whitmore, b. 27 Feb 1744/5.