On 10 Sep 1696 when Isaac was 25, he married
Margaret Miller, daughter of
Thomas Miller (ca 1609-14 Aug 1680) &
Sarah Nettleton (ca 1644-20 Mar 1726/7), in Middletown, CT.
Born on 12 Sep 1675 in Middletown, CT. Margaret died in Haddam, CT, on 31 Dec 1764; she was 89.