On 15 Jan 1848 when Francis was 21, he married
Elizbeth Mae McDonald Frazier, daughter of
Daniel Frazier &
Elizabeth Degarmo, in Marietta, Washington County, Ohio.
Born on 5 Dec 1829 in West Finley Township, Washington County, Pennsylvania. Elizbeth Mae McDonald died in London Mills, Fulton County, Illinois, on 10 Feb 1921; she was 91. Buried in Mount Auburn Cemetery, Saint Joseph.