On 17 Oct 1695 when James was 24, he married Hannah Harmon, daughter of Joseph Harmon (4 Jan 1646/7-28 Oct 1729) & Hannah Filley (ca 1653-28 Aug 1729), in Enfield, CT.128 Born 23 Feb 1674/5 in Suffield, CT.128 Hannah died in Enfield, CT on 19 Dec 1746.128

Children of James and Hannah (Harmon) Pease, born at Enfield:
    i. James Pease, b. 2 Feb 1696/7;
    ii. Anna Pease, b. 17 Apr 1699;
    iii. Hannah Pease, b. 18 Dec 1700;
    iv. Elizabeth Pease, b. 15 Jul 1703;
    v. Mary Pease, b. 20 Mar 1705/6;
    vi. Abigail Pease, b. 7 Jun 1708;
    vii. Sarah Pease, b. 17 Aug 1710;
    viii. Joseph Pease, b. 20 Jun 1713; and
    ix. Jemima Pease, b. 5 Jul 1716.128

On 9 Jun 1692 when Isaac was 19, he married Mindwell Osborn, daughter of John Osborn (10 Jan 1645/6-) & Abigail Eggleston (23 Jun 1648-30 Jul 1689), in Enfield, CT. Born 2 Jan 1673/4 in Windsor, CT. Mindwell died in Enfield, CT on 19 Aug 1731.

Children of Isaac and Mindwell (Osborn) Pease, born at Enfield:
    i. Isaac Pease, b. 2 May 1693, d. 8 Mar 1757, m. at Enfield 8 Nov 1722 Amie French, on 8 Nov 1722;
    ii. Abraham Pease, b. 2 Nov 1695, d. 2 Jun 1750 at Enfield, m. 3 Dec 1719 Mary Booth;
    iii. Isreal Pease, b. 2 May 1702, d. 14 Jan 1771 at Enfield, m. there 1726 Sarah Booth;
    iv. Ezekiel Pease, b. 20 Jun 1710;
    v. Timothy Pease, b. 12 Aug 1713;
    vi. Cummings Pease, b. 15 Nov 1715, d. 1808 at Longmeadow, MA, m. at Enfield 25 Sep 1755 Sarah Hale;
    vii. Benjamin Pease, b. 11 Dec 1707, d. 1768 at Enfield, m. there 19 Apr 1739 Abigail Rose;
    viii. Ann Pease, b. Feb 1704/5, d. 22 Oct 1773 at Enfield, m. there 3 Sep 1725 Nathaniel Prior;
    ix. Abigail Pease, b. 10 Jul 1699; and
    x. Mindwell Pease, b. ca. 1697.