On 24 Apr 1718 when Samuel was 24, he first married Mary Smith, daughter of Ebenezer Smith (15 Nov 1653-4 Nov 1744) & Mary, in New Haven, CT.56 Born on 1 Aug 1699 in New Haven, CT.56

Children of Samuel and Mary (Smith) Prindle, born at New Haven, include:
    i. Esther Prindle, b. 1 Feb 1718/9;
    ii. Moses Prindle, b. 4 Aug 1724; and
    iii. Joseph Prindle, b. 17 Jul 1730.55

Samuel second married Hannah.

On 15 Oct 1718 Joel married Jemima Benham, daughter of Nathan Benham (10 Jul 1679-Jun 1757) & Sarah Beecher (ca 1679-18 Dec 1712), in New Haven, CT.56 Born on 21 Sep 1700 in New Haven, CT.56 Jemima died in Cheshire, CT, on 8 Aug 1752; she was 51.55

Children of Joel & Jemima (Benham) Prindle, the first three at Wallingford, the last at New Haven:
    i. William Prindle, b. 2 Oct 1719;
    ii. Sarah Prindle, b. 9 Jul 1721, m. at wallingofrd 2 Oct 1744 Andrew Ives;
    iii. Lois Prindle, b. 21 Feb 1724; and
    iv. Joel Prindle, b. 16 Jan 1725/6.55

On 24 Jun 1724 when Hephzibah was 26, she married Abiel Roberts (28750) , son of Eli Roberts (ca 1653-Jun 1693) & Mary Mallory (12116) (28 Nov 1656-17 Sep 1752), in Wallingford, CT.90 Born on 10 Dec 1693 in New Haven, CT.56 Abiel died in Cheshire, CT, on 14 Jun 1786; he was 92.55

On 21 Dec 1726 Mary married John Bristol (16108) , son of John Bristol (6001) (4 Sep 1659-ca 1735) & Mercy Mansfield (26 Jul 1662-), in New Haven, CT.56 Born on 15 Jun 1706 in New Haven, CT.56 John died in Newtown, CT.