On 24 Nov 1718 Prudence first married James Chesebrough, son of Dr. Elisha Chesebrough (5 Apr 1667-1 Sep 1727) & Mary Minor (6 Oct 1671-29 Nov 1704). Born on 20 May 1699 in Stonington, CT.

On 21 Aug 1746 Prudence second married Daniel Brown (34254) , son of Thomas Brown (17368) (ca 1654-27 Dec 1723) & Hannah Collins (16312) (1 : 12 m : 1659 [1 Feb 1660]-), in North Stonington, CT. Born on 9 Oct 1696 in Stonington, CT. Daniel died in North Stonington, CT, on 30 Aug 1771; he was 74. Buried in Christopher Brown Farm.