On 24 Jul 1735 when James was 25, he first married
Lydia Eames, daughter of
Samuel Eames (15 Jan 1664/5-ca 1737) &
Patience Twitchell (2 Dec 1678-), in Framingham, MA.
Born on 1 May 1716 in Framingham, MA.441 Lydia died in Framingham, MA, on 8 Nov 1736; she was 20.