On 22 Feb 1777 when Amos was 21, he married Elizabeth Torrey, daughter of Noah Torrey & Elizabeth, in Fredericksburg, Putnam County, New York. Born on 1 Aug 1757 in Sharon, CT. Elizabeth died in 1818.

On 7 Dec 1780 David married Elizabeth Deming, daughter of Solomon Deming (8 Jul 1722-ca 1820) & Sarah Kirkham (15 Feb 1725/6-Feb 1818), in Canaan, CT. Born on 28 Apr 1754 in Canaan, CT. Elizabeth died in Greenfield, Saratoga County, New York, on 5 Jul 1801; she was 47.

Children of David and Elizaeth (Deming) Calkins, the first four born at Greenfield, the fifth at Wilton, Saratoga Co., NY:
    i. Elisha Deming Calkins, b. 6 Nov 1781;
    ii. Solomon Calkins, b. 20 Dec 1783;
    iii. Alva Calkins, b. ca. 1785;
    iv. Eli Calkins, b. 21 Apr 1786; and
    v. David Calkins, b. 18 Feb 1787.