On 4 Mar 1762 when Samuel was 27, he married Abigail Perigo, daughter of John Perigo & Hannah [Perigo], in Stonington, CT.211 Born on 8 Aug 1738 in Groton, CT. Abigail died in New London, CT, on 29 Jan 1822; she was 83.

Children of Samuel and Abigail (Perigo) Holdridge, born at Groton:
    i. Samuel Holdridge, b. 28 Oct 1763, m. Rhoda (b. 1 Nov 1764);
    ii. Nathaniel Holdridge, b. 19 Sep 1765;
    iii. Abigail Holdridge, b. 21 Sep 1767;
    iv. Cynthia Holdridge, b. 21 Sep 1769;
    v. Sabra Holdridge, twin, b. 21 Sep 1769, m. Robert Hempstead (son of Robert & Anne (Avery) Hempstead);
    vi. Isaac Holdridge, b. 25 Aug 1773;
    vii. Joseph Holdridge, b. 9 Mar 1775, m. at Groton 29 Jan 1795 Content Fish (b. ca. 1771);
    viii. Desire Holdridge, b. 17 May 1781; and
    ix. Content Holdridge, b. 20 Sep 1783.

Phineas married Mary Thompson, daughter of James Thompson (ca 1715/6-2 Jan 1808) & Mary Dixon (27 Nov 1723-). Born on 16 Nov 1746 in Stonington, CT. Mary died in Groton, CT, on 9 Nov 1814; she was 67. Buried in Holdredge Cemetery, Ledyard.

Children of Phineas & Mary (Thompson) Holdridge, born at Groton:
    i. Nathan Holdridge, b. 10 Jul 1760, d. 8 Oct 1817 at ledyard, m. Hannah Brown (b. 1774 at North Groton, d. 5 Dec 1848 at Ledyard, dau. of Nathaniel & Deborah (Morgan) Brown);
    ii. Phineas Holdridge, b. ca. 1763, d. 22 Jun 1854 at Ledyard;
    iii. Thompson Holdridge, b. ca. 1765, m. Betty Thompson, moved to Wayne, Ashtabula Co., OH;
    iv. Amos Holdridge, b. ca. 1772, m. Mar 1806 Philma Guild (b. 14 Aug 1788 at Leyden, MA, d. 1 May 1811, dau. of Samuel & Lydia (Esen) Guild);
    v. Nancy Holdridge, b. ca. 1776;
    vi. Phebe Holdridge, b. ca. 1780;
    vii. Mary Holdridge, b. ca. 1785;
    viii. Cynthia Holdridge, b. 1787, d. 21 Oct 1853; and
    ix. Sarah Holdridge, b. 1792, d. 8 May 1860 at Ledyard.

William married Phebe Burrows, daughter of Capt. John Burrows (13 Nov 1701-ca 1770) & Desire Packer (11 Sep 1712-ca 1808). Born on 29 Mar 1750 in Groton, CT. Phebe died in Pawtuxet, RI in 1825.