On 24 Mar 1736 when Ephraim was 21, he first married
Mary Osgood, daughter of
Dea. Hooker Osgood (26 Mar 1693-5 Jan 1765) &
Mary Wheelock (11 May 1695-8 May 1774), in Lancaster, MA.
Born on 7 Apr 1718 in Lancaster, MA. Mary died in Lancaster, MA, on 30 May 1738; she was 20.