On 19 Jan 1744 when Ephraim was 20, he married Elizabeth Cook (25977) , daughter of John Cook (19266) (5 Nov 1685-24 May 1754) & Alice Southworth (10210) (14 Jul 1688-25 Apr 1770), in Little Compton, RI.271 Ephraim of Little Compton & Elizabeth Cook of Tiverton were married by Richard Billings, Justice. Born ca 1725 in Tiverton, RI.316 Elizabeth died in Little Compton, RI in Apr 1797.271 Marriage intention published on 24 Nov 1743 at Little Compton, RI.271

When they were married, Ephraim was of Little Compton, Elizabeth of Tiverton. Their children, born at Little Compton:
    i. Jeremiah Richmond, b. 9 Aug 1744;
    ii. Lillis Richmond, b. Mar 1746;
    iii. Alice Richmond, b. Nov 1747;
    iv. Hannah Richmond, b. 1749;
    v. Gamaliel Richmond, b. 1751;
    vi. Ichabod Richmond, b. 1754;
    vii. Thomas Richmond, b. 1757;
    viii. James Richmond, b. 1760;
    ix. William Richmond, b. 10 Jul 1763, d. 19 Jan 1833; and
    x. Mary Richmond, b. 22 Sep 1765.