On 21 Dec 1776 when Isaac was 21, he married Mary Stetson (47279) , daughter of Caleb Stetson (30906) (ca 1734-10 Aug 1827) & Abigail Bradford (28877) (12 Jun 1732-31 Jan 1776), in Plympton, MA.284 Born on 7 Sep 1759. Mary died in Minot, Androscoggin County, Maine, on 3 Sep 1843; she was 83.