On 25 Jun 1711 Edward married Bridget Bosworth in Hull, MA. Born on 2 Jun 1691 in Hull, MA.
Children of Edward and Bridget (Bosworth) Southworth:
i. Constant Southworth, b. 25 Jul 1712, m. 15 Apr 1734 Martha Keith;
ii. Bridget Southworth, b. 3 Apr 1714;
iii. Ebenezer Southworth, b. 13 Aug 1716, m. Elizabeth;
iv. Edward Southworth, b. Dec 1718, m. 16 Dec 1750 Lydia Packard;
v. Theophilus Southworth, b. 10 Feb 1719/20, d. after 1775;
vi. Sarah Southworth, b. 16 Jan 1722/3, m. 25 May 1745 Peter Edson;
vii. Benjamin Southworth, b. 17 Apr 1728, d. ca 1800 at Bridgewater, MA, m. 3 Mar 1763 Mary Smith;
viii. Lemuel Southworth, b. 17 Apr 1728, m. 6 Nov 1757 Patience West; and
ix. Mary Southworth, b. 2 Jan 1730/1, m. at Hull 31 Oct 1751 Eliphalet Jones.