On 26 Nov 1722 when John was 26, he first married Jemima Shed, daughter of John Shed (1 Apr 1654-31 Jan 1736/7) & Sarah Chamberlain (18 Jan 1655/6-17 Jan 1735/6), in Billerica, MA. Born 18 Jan 1698/9 in Billerica, MA.448 Jemima died in Billerica, MA on 14 Sep 1740.448

In Jun 1742 John second married Mary Shed.164 Born on 7 Dec 1689 in Billerica, MA.

According to George Walter Chamberlain, Mary, the wife of Abraham Chamberlain, was not the Mary Shed born 7 Dec 1689, daughter of John and Sarah (Chamberlain) Shed.448

Children of Abarahm and Mary (Shed) Chamberlain:
    i. Mary b. 28 Dec 1718, d. young;
    ii. Abraham, b. 25 Aug 1720;
    iii. Benjamin, b. 18 Oct 1722;
    iv. John, b. 19 Mar 1724/5;
    v. Nathan, b. 18 mar 1726/8;
    vi. Zaccheus, b. 19 Sep 1729;
    vii. Tabitha, twin, b. 19 Sep 1729; and
    viii. Mary, b. 16 Oct 1734.164

On 2 Apr 1745 when Dorcas was 33, she married Ebenezer Wyman (27976) , son of Timothy Wyman (11604) (15 Sep 1661-9 Jan 1708/9) & Hannah Wiswall (6 Feb 1661/2-17 Aug 1743), in Billerica, MA. Born on 21 Mar 1706 in Woburn, MA. Ebenezer died in Townsend, MA, on 21 Oct 1760; he was 54.

Ebenezer first married Rebecca Johnson, second Dorcas Wilson.