On 13 Aug 1751 when Charles was 30, he married Ann Camp (32180) , daughter of Hezekiah Camp (14944) (25 Mar 1700-24 Nov 1791) & Lydia Clark (ca 1703-3 Nov 1777), in Salisbury, CT. Born 2 Feb 1731/2 in Milford, CT. Ann was baptized in First Church of Milford, 31 Mar 1731/2.64 Ann died in Salisbury, CT on 8 Mar 1758.

Children of Charles and Ann (Camp) Chapin, born at Salisbury:
    i. Charles Chapin, b. 26 Jun 1752;
    ii. Ann Chapin, b. 17 Aug 1754, m. Elijah Gates of Lenox; and
    iii. Phineas Chapin, b. 16 Feb 1757, d. 12 Feb 1816.