On 20 Dec 1807 when Isaac was 22, he married Lettice Barker (50730) , daughter of Joshua Barker (33598) (ca 1740-22 Dec 1804) & Mary Copeland (44684) (3 Nov 1740-27 Jan 1828), in Pembroke, MA.395 Born on 22 Mar 1785.290 Lettice died on 12 Apr 1863; she was 78.290

Children of Isaac and Lettice (Barker) Hobart, born at Pembroke:
    i. Desire Standish Hobart, b. 16 Aug 1808;
    ii. Israel Hobart, b. 12 Jul 1811;
    iii. Lettice Barker Hobart, b. 4 Mar 1814; and
    iv. Joseph Barker Hobart, b. 5 May 1816.