On 3 Apr 1755 when Ephraim was 21, he married Lucretia Locke (56229) , daughter of Samuel Locke (24 Aug 1702-13 Apr 1775) & Rebecca Richardson (42050) (14 Jul 1710-20 Sep 1789).279 Born on 5 Nov 1733 in Woburn, MA.279 Lucretia died in Sterling, MA, on 29 Dec 1816; she was 83.279