On 20 Sep 1753 when Leicester was 23, he married Esther Weld (43665) , daughter of John Weld (23911) (ca 1690-24 Jul 1763) & Esther Waldo (50569) (3 Jan 1698-11 Jan 1777), in Pomfret, CT. Born on 30 Jul 1728 in Pomfret, CT.54 Esther died in Fairfax, Franklin County, Vermont, on 14 Sep 1810; she was 82.

Children of Leicester and Ester (Weld) Grosvenor, born at Pomfret:
    i. Theophilus Grosvenor, b. 29 Jul 1755, d. 8 Oct 1797 at Fairfax, VT, m. at Windsor 28 Oct 1784 Bathsheba Thornton (b. 20 Jul 1765 at Lanesboro, MA, d. 8 mar 1803 at Fairfax);
    ii. Resolved Grosvenor, b. 27 Aug 1757, d. 6 Mar 1831 at Fairfax, m. at Chesterfield, MA, 19 Sep 1785 Elizabeth Stephenson (b. 29 Jun 1757 at Cohasset, MA, d. 27 Aug 1841 in Franklin Co., VT, dau. of John & Martha (Nichols) Stephenson), also m. Amelia Orden (d. Oct 1796);
    iii. Esther Grosvenor, b. 9 Aug 1759, d. at Marietta, Washington Co., OH, m. at Hardwick, MA 17 May 1786 Benjamin Converse (b. 14 Sep 1746 at Thompson, CT, c. 1790 at Marietta, Washington Co., OH, son of James & Mary (Leavens) Converse);
    iv. Leicester Grosvenor, b. 11 Aug 1761, d. 26 Apr 1827 at Fairfax, m. 10 Dec 1783 Sarah Safford (b. 24 mar 1766 at Morristown, VT, d. 25 Jul 1824 at Fairfax, dau. of Ankum Safford);
    v. Rebecca Grosvenor, twin, b. 11 Aug 1761, m. at Williamstown, MA 20 may 1790 John Newbery, resided at Stockton, Chautauqua Co., NY;
    vi. Daniel Grosvenor, b. ca. 1763;
    vii. Richard Grosvenor, b. 6 Apr 1765, d. 12 Aug 1838 at Stockton, m. ca. 1793 Rebecca Gloyd (b. 19 Aug 1764 at Abington, d. 13 Jul 1827 at Stockton, dau. of John & Silence (Bate) Glyde, also spelled Gloyd);
    viii. Mary Grosvenor, b. 3 Jun 1768, d. 11 Jan 1815 at Chittenden, VT, m. Jesse Gloyd (b. 17 Apr 1770 at Abiington, MA, d. 30 Oct 1847, brother of Rebecca who married Mary’s older brother Richard); and
    ix. Lucy Grosvenor, b. 15 Nov 1770, d. 25 Feb 1844 at Stockton, m. Samuel Crissey (b. 2 mar 1770 at Stamford, CT, d. 1 Mar 1848 at Stockton, son of John & Martha (Davenport) Crissey).