On 20 Jan 1725 when Restcomb was 20, he first married Elizabeth Lake (20819) , daughter of David Lake (7656) (2 Jun 1679-4 Aug 1767) & Mary Wilcox (19276) (25 Feb 1682-6 May 1747), in Little Compton, RI.374,271 Restcome Sanford and Elizabeth Lake were married by Thomas Church, Justice, 29 Dec 1724. Born ca 1706. Elizabeth died in Tiverton, RI on 6 May 1747.374 Marriage intention published on 29 Dec 1714 at Tiverton, RI.374

Children of Restcome and Elizabeth (Lake) Sanford, born at Tiverton:374
    i. William Sanford, b. 17 Jun 1725, m. Mary Waight (b. 1722);
    ii. Restcome Sanford, b. 19 Jun 1727, m. at Portsmouth 16 Apr 1752 Ruth Sanford;
    iii. Abigail Sanford, b. 19 Feb 1729, d. 6 Dec 1736;
    iv. David Sanford, b. 28 Sep 1730, d. 27 Nov 1736;
    v. Peleg Sanford, b. 24 Jan 1733, d. 10 Dec 1736;
    vi. Mary Sanford, b. 24 Sep 1735, m. at Tiverton 9 Nov 1760 Samuel Borden, (b. 1735, son of Joseph Borden & Abigail Russel);
    vii. Samuel Sanford, b. 11 Oct 1737, d. 8 Sep 1738;
    viii. Deborah Sanford, b. 23 Dec 1739, m. Constant Hart (b. 1744); and
    ix. Sarah Sanford, b. 7 Nov 1741, m. George Tabor (b. 1741).

Restcomb second married Content.

Children of Restcome and Content Sanford, born at Tiverton:374
    i. Elizabeth Sanford, b. 18 Feb 1743;
    ii. George Sanford, b. 17 Oct 1750; and
    iii. Ephraim Sanford, b. 28 May 1752.