On 25 May 1829 when Mary Isabella was 22, she married William Means Kearns, son of Thomas Kearns (24 Aug 1779-13 May 1854) & Mary Greer (20 May 1780-7 Sep 1858), in Wayne County, Ohio. Born on 12 Nov 1805 in Elizabeth Township, Allegheny County, Pennsylvania. William Means died in Chepstow, Washington County, Kansas, on 12 Apr 1882; he was 76. Buried in Chepstow Cemetery.

1850 Federal Census. St Joseph Township, Williams County, Ohio
Roll 741, page 78A
    William Kearns, 45, farmer, $600 real estate, b. PA
    Mary Kearns, 43, b. PA
    Thomas Kearns, 17, farmer, b. OH
    Mary Kearns, 16, b. OH
    Theadore Kearns, 15, farmer, b. OH
    Susannah Kearns, 14, b. OH
    Issabel Kearns, 13, b. OH
    William Kearns, 10, b. OH
    Martha Kearns, 8, b. OH
    John Kearns, 6, b. OH
    James Kearns, 4, b. OH
    Franklin Kearns, 1, b. OH

1870 Federal Census. Marengo, Iowa County, Iowa
Roll 396, page 300B
    William M. Kearns, 63
    Mary Kearns, 63
    Susan Kearns, 30
    James Kearns, 24
    Franklin Kearns, 21

1880 Federal Census. Marengo, Iowa County, Iowa
Roll 345, page 171A
    William Kearns, 74, farmer, b. PA, father b. MD, mother b. PA
    Mary Kearns, 73, wife, housekeeping, b. OH, parents b. PA
    Susan Kearns, 40, daughter, single, school teacher, b. OH, father b. PA, mother b. OH
    Mary Thompson, 28, widowed, housekeeping, b. OH, father b. PA, mother b. OH

Chepstow Cemetery, Washington County, Kansas
    Wm. M. Kearns, d. 30 Apr 1882, æ. 76 y 6 m 18 d
    Mary, wife of Wm. K. Kearns, d. 26 Nov 1889, æ. 82 y 7 m 23 d