On 9 Dec 1781 when Isaac was 34, he first married
Catherine Smith, daughter of
Rev. Thomas Smith (6 Feb 1705/6-7 Jul 1788) &
Judith Miller (23 Aug 1716-1 Jul 1785), in Pembroke, MA.
395 Born on 21 Mar 1756 in Pembroke, MA. Catherine died in Hanson, MA, on 26 Mar 1785; she was 29.